This guidance sets out how prosecutors should approach cases where there is an allegation that the suspect has intentionally or recklessly transmitted an infection to another person during sexual activity. It excludes other methods of transmission, such as shared needle usage. Any allegation of intentional or reckless transmission of an STI will almost invariably be eligible for early advice in accordance with Chapter 7 and Annex 6 of the Director’s Guidance on Charging (sixth edition).